Alignments
We have currently 15 alignments in our library (for ATM, BRCA1, BRCA2, CHEK2, TP53, MLH1, MRE11, MSH2, MSH6, NBN, PALB2, PMS2, RAD50, RAD51 and XRCC2)
- - ATM for which the 9 following sequences were used:
(Click here to see ATM alignment (last updated 2008/10/28)) - * Homo sapiens
- * Mus musculus (mouse)
- * Sus scrofa (pig)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Gallus gallus (chicken)
- * Xenopus laevis (frog)
- * Danio rerio (zebrafish)
- * Branchiostoma floridae (lancelet)
- * Strongylocentrotus purpuratus (purple sea urchin)
- - BRCA1 for which the 13 following sequences were used:
(Click here to see BRCA1 alignment (last updated 2007/11/08)) - * Homo sapiens
- * Pan troglodytes (chimpanzee)
- * Gorilla gorilla
- * Pongo pygmaeus (orangutan)
- * Macaca mulatta (monkey)
- * Mus musculus (mouse)
- * Canis lupus familiaris (dog)
- * Bos taurus (cow)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Gallus gallus (chicken)
- * Xenopus laevis (frog)
- * Tetraodon nigroviridis (pufferfish - green spotted)
- * Strongylocentrotus purpuratus (purple sea urchin)
- * Pan troglodytes (chimpanzee)
- - BRCA2 for which the 12 following sequences were used:
(Click here to see BRCA2 alignment (last updated 2007/11/08)) - * Homo sapiens
- * Pan troglodytes (chimpanzee)
- * Macaca mulatta (monkey)
- * Rattus norvegicus (rat)
- * Canis familiaris (dog)
- * Canis lupus familiaris (dog)
- * Bos taurus (cow)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Gallus gallus (chicken)
- * Xenopus laevis (frog)
- * Tetraodon nigroviridis (pufferfish - green spotted)
- * Fugu rubripes (Pufferfish - fugu)
- * Strongylocentrotus purpuratus (purple sea urchin)
- * Pan troglodytes (chimpanzee)
- - CHEK2 for which the 13 following sequences were used:
(Click here to see CHEK2 alignment (last updated 2010/06/04)) - * Homo sapiens
- * Mus musculus (mouse)
- * Canis familiaris (dog)
- * Bos taurus (cow)
- * Loxodonta africana (elephant)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Ornithorhynchus anatinus (platypus)
- * Gallus gallus (chicken)
- * Xenopus laevis (frog)
- * Danio rerio (zebrafish)
- * Strongylocentrotus purpuratus (purple sea urchin)
- * Ciona intestinalis (sea quirt - tunicate)
- * Drosophila melanogaster (fruitfly)
- * Mus musculus (mouse)
- - TP53 for which the 11 following sequences were used :
(Click here to see TP53 alignment (last updated 2020/11/30)) - * Homo sapiens
- * Pongo abelii (orangutan)
- * Macaca mulatta (monkey)
- * Callithrix jacchus (marmoset)
- * Mus musculus (mouse)
- * Bos taurus (cow)
- * Sarcophilus harrisii (Tasmanian devil)
- * Anolis carolinensis (lizard)
- * Xenopus laevis (frog)
- * Latimeria chalumnae (coelacanth)
- * Danio rerio (zebrafish)
- * Pongo abelii (orangutan)
- - MLH1 for which the 14 following sequences were used:
(Click here to see MLH1 alignment (last updated 2012/08/13)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Mus musculus (mouse)
- * Canis lupus familiaris (dog)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Gallus gallus (chicken - aves)
- * Xenopus laevis (frog - amphibia)
- * Danio rerio (zebrafish - teleostei)
- * Petromyzon marinus (lamprey eel - agnatha)
- * Ciona intestinalis (sea quirt - urochordata)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Nematostella vectensis (starlet anemone - cnidaria)
- * Trichoplax adhearens (placozoa)
- * Macaca mulatta (monkey)
- - MRE11 for which the 16 following sequences were used :
(Click here to see MRE11 alignment (last updated 2013/10/31)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Callithrix jacchus (marmoset)
- * Mus musculus (mouse)
- * Sus scrofa (pig)
- * Loxodonta africana (elephant)
- * Dasypus novemcinctus (armadillo)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Ornithorhynchus anatinus (ornithorhynch)
- * Gallus gallus (chicken - aves)
- * Anolis carolinensis lizard)
- * Xenopus tropicalis (frog - amphibia)
- * Latimeria chalumnae (coelacanth)
- * Fugu rubripes (pufferfish - fugu)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Macaca mulatta (monkey)
- - MSH2 for which the 14 following sequences were used:
(Click here to see MSH2 alignment (last updated 2012/08/13)) - * Homo sapiens
- * Cercopithecus aethiops (monkey)
- * Mus musculus (mouse)
- * Bos taurus (cow)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Gallus gallus (chicken)
- * Xenopus laevis (frog)
- * Danio rerio (zebrafish)
- * Petromyzon marinus (lamprey eel - agnatha)
- * Ciona intestinalis (sea quirt - tunicate)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Nematostella vectensis (starlet anemone - cnidaria)
- * Trichoplax adhearens (placozoa)
- * Cercopithecus aethiops (monkey)
- - MSH6 for which the 14 following sequences were used:
(Click here to see MSH6 alignment (last updated 2012/08/13)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Mus musculus (mouse)
- * Bos Taurus (cow - laurasiatheria)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Gallus gallus (chicken - aves)
- * Xenopus laevis (frog - amphibia)
- * Danio rerio (zebrafish - teleostei)
- * Petromyzon marinus (lamprey eel - agnatha)
- * Ciona intestinalis (sea quirt - urochordata)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Nematostella vectensis (starlet anemone - cnidaria)
- * Trichoplax adhearens (placozoa)
- * Macaca mulatta (monkey)
- - NBN for which the 16 following sequences were used :
(Click here to see NBN alignment (last updated 2013/10/31)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Callithrix jacchus (marmoset)
- * Mus musculus (mouse)
- * Bos Taurus (cow - laurasiatheria)
- * Loxodonta africana (elephant)
- * Dasypus novemcinctus (armadillo)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Ornithorhynchus anatinus (ornithorhynch)
- * Gallus gallus (chicken - aves)
- * Anolis carolinensis lizard)
- * Xenopus tropicalis/laevis (frog - amphibia)
- * Latimeria chalumnae (coelacanth)
- * Danio rerio (zebrafish - teleostei)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Macaca mulatta (monkey)
- - PALB2 for which the 10 following sequences were used :
(Click here to see PALB2 alignment (last updated 2014/09/18)) - * Homo sapiens
- * Pan troglodytes (chimpanzee)
- * Mus musculus (mouse)
- * Canis lupus familiaris (dog)
- * Bos taurus (cow - laurasiatheria)
- * Equus caballus (horse)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Gallus gallus (chicken - aves)
- * Xenopus tropicalis/laevis (frog - amphibia)
- * Danio rerio (zebrafish - teleostei)
- * Pan troglodytes (chimpanzee)
- - PMS2 for which the 14 following sequences were used:
(Click here to see PMS2 alignment (last updated 2012/08/13)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Mus musculus (mouse)
- * Bos Taurus (cow - laurasiatheria)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Gallus gallus (chicken - aves)
- * Xenopus tropicalis (frog - amphibia)
- * Danio rerio (zebrafish - teleostei)
- * Petromyzon marinus (lamprey eel - agnatha)
- * Ciona intestinalis (sea quirt - urochordata)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Nematostella vectensis (starlet anemone - cnidaria)
- * Trichoplax adhearens (placozoa)
- * Macaca mulatta (monkey)
- - RAD50 for which the 16 following sequences were used :
(Click here to see RAD50 alignment (last updated 2013/10/31)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Callithrix jacchus (marmoset)
- * Mus musculus (mouse)
- * Bos Taurus (cow - laurasiatheria)
- * Loxodonta africana (elephant)
- * Dasypus novemcinctus (armadillo)
- * Monodelphis domestica (gray short-tailed opossum - marsupialia)
- * Ornithorhynchus anatinus (ornithorhynch)
- * Gallus gallus (chicken - aves)
- * Anolis carolinensis lizard)
- * Xenopus tropicalis/laevis (frog - amphibia)
- * Latimeria chalumnae (coelacanth)
- * Danio rerio (zebrafish - teleostei)
- * Branchiostoma floridae (lancelet - cephalochordate)
- * Strongylocentrotus purpuratus (purple sea urchin - echinodermata)
- * Macaca mulatta (monkey)
- - RAD51 for which the 15 following sequences were used:
(Click here to see RAD51 alignment (last updated 2012/03/20)) - * Homo sapiens - with Accession Nb: NP_002866_RAD51
- * Mus musculus (mouse) - with Accession Nb: NP_035364_RAD51
- * Rattus norvegicus (rat) - with Accession Nb: NP_001102674_RAD51
- * Oryctolagus cuniculus (rabbit) - with Accession Nb: NP_001075493_RAD51
- * Canis familiaris (dog) - with Accession Nb: NP_001003043_RAD51
- * Bos taurus (cow) - with Accession Nb: NP_001039644_RAD51
- * Sus scrofa (pig) - with Accession Nb: NP_001116653_RAD51
- * Monodelphis domesticus (grey, short tailed opossum) - with Accession Nb: RAD51_XP_001370830
- * Gallus gallus (chicken) - with Accession Nb: NP_990504_RAD51
- * Xenopus laevis (frog) - with Accession Nb: RAD51_NP_001081236
- * Danio rerio (zebrafish) - with Accession Nb: NP_998371_cor_RAD51
- * Branchiostoma floridae (lancelet) - with Accession Nb: cDNA_pep
- * Ciona intestinalis (sea quirt - tunicate) - with Accession Nb: RAD51_XP_002126934
- * Strongylocentrotus purpuratus (purple sea urchin) - with Accession Nb: RAD51_XP_788683
- * Drosophila melanogaster (fruitfly) - with Accession Nb: RAD51_NP_524583
- * Mus musculus (mouse) - with Accession Nb: NP_035364_RAD51
- - XRCC2 for which the 15 following sequences were used:
(Click here to see XRCC2 alignment (last updated 2011/10/03)) - * Homo sapiens
- * Macaca mulatta (monkey)
- * Mus musculus (mouse)
- * Canis familiaris (dog)
- * Loxodonta africana (elephant)
- * Monodelphis domesticus (grey, short tailed opossum)
- * Ornithorhynchus anatinus (ornithorhynch)
- * Gallus gallus (chicken)
- * Anolis carolinensis (lizard)
- * Xenopus tropicalis
- * Danio rerio (zebrafish)
- * Branchiostoma floridae (lancelet)
- * Strongylocentrotus purpuratus (purple sea urchin)
- * Nematostella vectensis (starlet anemone)
- * Trichoplax adhaerens (trichoplax)
- * Macaca mulatta (monkey)
Click here to see BRCA1 and BRCA2 TSMR demonstration